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A federal panel will get its first look next week at a proposal to use the revolutionary gene-editing technology CRISPR in humans, in this case to try to treat cancer.

The experiment, proposed by the University of Pennsylvania, would remove certain cells of the immune system, called T cells, from cancer patients. Scientists would then use CRISPR to genetically modify the T cells so that when they’re returned to the patient, they target and destroy myeloma, melanoma, and sarcoma tumor cells.

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Carrie Wolinetz, the associate director for science policy at the National Institutes of Health, disclosed the review in a blog post, which was first reported by MIT Technology Review. The federal panel must review all human experiments that alter DNA.

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