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In a step that could lead to a new diabetes treatment, several Boston-area hospitals have teamed up with the Harvard Stem Cell Institute and biotech Semma Therapeutics to make personalized cell-based therapies and organize clinical trials.

It is one of several initiatives around the country aimed at manufacturing cell-derived treatments, as the hope for such therapies creates a demand for the production of the cells.


In patients with type 1 diabetes, the immune system attacks the pancreatic cells that produce insulin, called beta cells. Doctors have for years transplanted beta cells from dead donors into patients, but the supply is insufficient for the millions of people with type 1 diabetes, and patients’ bodies sometimes reject the donor cells.

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  • I have been a type 1 diabete for over 50 years. i would like to find out how to get enrolled in the clinical trials for islets. Where would I go to get signed up.

  • I have had type1 diabetes sense I was 11yr. Old. I work hard everyday to keep my sugar as level as possible but it’s so hard and never stays level.
    I am healthy, I don’t smoke or drink. I eat healthy and walk daily.
    I would love the opportunity to be part of your stem cell research and would be so grateful for the chance to be a volunteer in your program.
    Thank for your dedication and hard work to fond a cure for this dreaded disease.

  • I have a loved one suffering from being diabetic type 1 and has already under gone a transplant of the pancreas and kidneys. His pancreas is no longer functioning and making beta cells assuming his immune system finally destroyed all the cells and is again a full on Diabetic with glucose levels hard to maintain and worried how much longer he will have his eye sight, how long his transplanted kidneys will hold and the neuropathy is getting worse. He’s really not looking forward going through full dialyses again as he has already experienced this all too well before the transplants.

    I have spent hours researching the breakthrough of curing this disease and believe replacing beta cells with steam cell is the way to go as long as there has been a way to get the body not to attack the new cell transplant.

    So i guess the question is… How do we participate in the clinical trials so maybe we can be one of the few first success stories? Or please refer us to a clinic that is do human trials. We need the help

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