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An experimental drug touted as a breakthrough for treating severe postpartum depression is showing some promising results in a small clinical trial.

Sage Therapeutics, based in Cambridge, Mass., reported on Tuesday that 7 of the 10 women who took the drug in the trial experienced significant improvement in their depression within 60 hours of the injection. That effect was maintained for 30 days.


Among the 11 women who took the placebo, just one experienced remission within 60 hours.

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  • As a 67 year old woman and grandmother, I feel compelled to comment….in 1976 I suffered from severe postpartum depression, and in those days, no one did anything despite reporting it to your obstetrician! I was severe enough to be hospitalized, but at the time I just profoundly suffered. It is a Godsend that there are meds now and HELP for an illness that you truly feel shame and condemnation. God Help PPD sufferers. Thank you

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