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There’s much about the business of medicine that is praiseworthy and inspiring. From fighting superbugs, to trying to solve Alzheimer’s, to exploring our many microbes, there are a lot of big, important problems out there for drug companies to solve.

But medicine is big business and sometimes drug companies, in the pursuit of profits, pull shenanigans.

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In this episode of “Signal,” we take a deep dive into some of the nefariously creative tricks drug companies use to maintain monopolies and handle competition. These tricks, often played around patents, can cost the health care system — and we the insurance premium payers and taxpayers — billions.

Listen and learn a few of the questionable tricks of the trade. Meet the “hard switch,” “tricks are for kids,” and “pay for delay.”

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The podcast is produced by Jocelyn Gonzales.

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