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Four patients have died of liver toxicity while being treated with an experimental cancer drug from Seattle Genetics — leading the US Food and Drug Administration to place a handful of the company’s early stage clinical trials involving the treatment on hold.

The drug, called vadastuximab talirine, was being tested in patients with acute myeloid leukemia — a cancer of the blood and bone marrow. More than 300 patients have been tested with this drug thus far, the company said in a statement.

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  • How effective is immunotherapy on a “trapped” lung, tumor included? The lung is behind a literal wall of fluid in the pleural cavity, up against the heart…the result of this effusion was brought on by one infusion of
    a chemo called Novelbean. I also mention that the other “good” lung now has a growth that can not only be
    seen on a CT scan, but can also be seen & felt by the hand (it’s about the size of a lime). This is my husband.

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