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Forty years ago, one of Dr. Stephen Hauser’s first patients was a young Harvard Law School graduate and White House aide with a case of multiple sclerosis that raced like a brush fire through her brain. She quickly lost her ability to speak, swallow, and breathe. She got married in a wheelchair in her hospital room, tethered to breathing and feeding tubes and dressed in her wedding gown.

“We had nothing to treat her with,” recalled Hauser, now director of the Weill Institute for Neurosciences at the University of California, San Francisco. It was such a searing moment for the young doctor, then at the beginning of his neurology training, that he decided to dedicate his career to MS research.

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  • Were SPMS patients studied at any point during ocrelizumab’s protracted development?
    It has been apparent to some of us for many years that different demyelinating diseases, historically lumped under the MS label, are responsible for the wide variations in form, course, treatment response and outcome.

  • I have relapsing-remitting MS diagnosed in 2000. I’m 68 years old and just recently seeing a change in my left leg and how it functions. Slowly changes have occurred, over my 17 years of knowledge of this disease but it is embarrasing now that I need to drag along my left foot when walking. Wondering if this new drug might help or stop this from getting worse.???


  • I am so encouraged. I hv had
    MS 30 yrs diagnosed but 4 yrs
    before having symptoms. Went
    To new dr. at Vanderbilt on wed 3-29-17 told I would be good candidate for new drug
    for progressive MS and it was
    approved Thur. 3-30-17. It’s been a long battle and slow
    decline. The only exercise I
    get is the water which I hv
    done for 29 yrs. but is getting
    much harder to get there. I
    feel so blessed after many yrs.
    of prayer there is something
    that might help! May God Bless all of u.

  • Thank you for providing a very comprehensive article about this new drug but also the history, expected cost and how the B cell discovery could change ms research. As someone with PPMS, I’ve watched this drug and the trials closely. You provide one of the most succinct articles that I’ve read on the drug and future potential of this discovery. Thank you.

  • This is Rituximab rebranded, for the sake of keeping the patent active. Rituximab is used as part of the treatment protocol for some of the HSCT facilities that treat MS and other Autoimmune diseases. This is NOT NEW! They should be focusing on further research for HSCT for MS and other Autoimmune Diseases. Then the majority of people with MS etc. will be a lot better off.

  • I’m also very interested I’m a 48 year old woman with Rrms and also take Tecidera it’s getting more n more difficult each day I was Dx in 2011 after many years of testing. Please feel free to contact me I need some relief. Thank you

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