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President Trump wants to carve a whopping $5.8 billion out of the National Institutes of Health’s budget next year. But he’s handcuffed in one regard: He can’t touch the big science projects that President Obama launched.

That’s because Congress last year overwhelmingly passed the 21st Century Cures Act, which guarantees NIH $4.8 billion over the next 10 years. The vast majority of that money is earmarked for a trio of Obama’s signature initiatives — and Congress has shown no signs of backing away from those appropriations.

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