LOS ANGELES — Here in this hotspot for unregulated stem cell clinics, you don’t have to drive far to find a doctor offering unproven treatments for a bum knee involving stem cells derived from a patient’s own fat.

In his lab here at the University of Southern California, Dr. Denis Evseenko wants to tackle knee problems with stem cells, too — but he’s a world away in his philosophy. He’s taking a stab at something much more ambitious. And he’s doing it by the book.

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