At first glance, the landmark experiments using CRISPR to correct a mutation in human embryos represent a breakthrough, since they demonstrated three key things: that CRISPR can delete the gene it’s supposed to in a viable embryo, that it can make the change in a way that causes all of an embryo’s cells to have it (when some embryo cells but not others have their DNA changed it’s called mosaicism and would be a problem), and that CRISPR can do this with few if any unintended edits, or off-target effects.

But when STAT spoke to the lead scientist, reproductive biologist Shoukhrat Mitalipov of Oregon Health and Science University, two days before his study was published in Nature, he had a different view on his experiment.

Unlock this article by subscribing to STAT Plus and enjoy your first 30 days free!

GET STARTED

What is it?

STAT Plus is STAT's premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis. Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond.

What's included?

  • Daily reporting and analysis
  • The most comprehensive industry coverage from a powerhouse team of reporters
  • Subscriber-only newsletters
  • Daily newsletters to brief you on the most important industry news of the day
  • Online intelligence briefings
  • Frequent opportunities to engage with veteran beat reporters and industry experts
  • Exclusive industry events
  • Premium access to subscriber-only networking events around the country
  • The best reporters in the industry
  • The most trusted and well-connected newsroom in the health care industry
  • And much more
  • Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr.

Leave a Comment

Please enter your name.
Please enter a comment.

Sign up for our Daily Recap newsletter

A roundup of STAT’s top stories of the day in science and medicine

Privacy Policy