A group of prominent scientists, including pioneers in genome-editing, have questioned the key finding of a headline-making study in which researchers reported using CRISPR to repair a disease-causing gene in viable human embryos.

In the new, unpublished paper, posted this week to the biology preprint site bioRxiv and not yet peer-reviewed, scientists led by Maria Jasin of Memorial Sloan Kettering Cancer Center took aim at a startling claim in the embryo study.

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