gene therapy from Voyager Therapeutics (VYGR) delivered surgically into the brains of patients with advanced Parkinson’s disease reduced their need for standard Parkinson’s medications and improved motor function, according to results from a small, early-stage clinical trial reported Wednesday.

Unlike most gene therapies for inherited disease in clinical development, the Voyager treatment does not aim to cure Parkinson’s — because nothing yet invented can fully prevent the loss of neurons in the brain. Instead, Voyager’s gene therapy acts like a biological detour around dead neurons, so Parkinson’s patients respond better and longer to levodopa, the standard drug used to keep motor function under control.

This is a STAT Plus article and you can unlock it by subscribing to STAT Plus today. It's easy! Your first 30 days are free and if you don't enjoy your subscription you can cancel any time.
Already a subscriber? Log in here.

Leave a Comment

Please enter your name.
Please enter a comment.

Sign up for our Morning Rounds newsletter

Your daily dose of what’s new in health and medicine.