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WASHINGTON — Senate leaders on Wednesday announced a bipartisan budget agreement that would increase funding for the National Institutes of Health by $2 billion and raise spending meant to address the opioid and mental health crisis by $6 billion over the next two years.

The White House endorsed the agreement during its announcement on the Senate floor. The House is likely to pass it with few changes, staving off another government shutdown or continuing spending resolution that had loomed if no agreement was reached.

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