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In 1995, when Anthony Bellotti was 17 and slogging through a summer internship in an animal research lab, he was struck not by how the work could help the millions of people suffering from heart disease, but by the plight of the pigs being hoisted by their hind legs onto tables.

“They were always screaming,” he said. “I thought, ‘Something’s wrong with this picture.’”

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He still hoped to one day join his father in the medical field, but the experience triggered a more lasting ambition: rolling back animal testing, which helped refine vaccines that saved millions from polio and smallpox, among others, as well as treatments for many other diseases.

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