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Boston biotechnology startup that uses plastic chips to simulate human organs to test medicines outside of the body said Tuesday that two more pharmaceutical giants and a major California teaching hospital plan to use its technology to develop drugs.

Emulate, which makes so-called organ-on-a-chip systems to test whether drugs are safe and effective, announced partnerships with Japan-based Takeda Pharmaceutical (TKPYY), Swiss-based Roche (RHHBY), and Cedars-Sinai Medical Center, of Los Angeles.

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