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This week could be pivotal for the fate of the popular influenza vaccine known as FluMist and its manufacturer MedImmune, a division of AstraZeneca.

On Wednesday, the Advisory Committee on Immunization Practices will hear a pitch the company hopes will persuade it to restore its recommendation for use of FluMist, the only non-injectable flu vaccine licensed in the United States.

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The panel declined to offer its backing of FluMist for the last two years because of concerns it isn’t protecting against H1N1 flu viruses. That effectively sidelined the vaccine here for the current and the previous flu seasons.

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