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WASHINGTON — Key Senate Republicans have signaled an increasing interest in making changes to the so-called 340B drug discount program, adding to a chorus of House Republicans who are pushing to overhaul the program.

The Senate Health, Education, Labor and Pensions Committee met Thursday to discuss the program with representatives of the hospitals who favor the program and the pharmaceutical companies who have long called for reining it in. The hearing was the first sign of serious Senate interest in the issue, and it follows a string of relatively heated meetings in the House Energy and Commerce Committee and a flurry of bill introductions on the topic from lawmakers in both chambers and both parties.

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