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WASHINGTON — Two Food and Drug Administration directors will retire this week, according to the agency.

The departures leave three of the FDA’s 19 drug review divisions without permanent leaders.

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Dr. Curtis Rosebraugh, who runs an office that oversees three drug review divisions, will be leaving the FDA. Also retiring is Dr. Donna Griebel, who directs the division that reviews drugs for gastrointestinal disease and some metabolic diseases. Both are retiring effective Saturday; neither returned a request for comment.

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