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For decades, Americans living with diabetes have been relying on injections of insulin to manage their illness. Those injections can be painful — and inconvenient.

Two new developments — one a newly released study and the other the publication of new clinical trial data — describe advances toward an alternative approach: the delivery of blood-sugar-regulating hormones in a pill, long regarded as the “holy grail” of diabetes treatment.


The study, conducted by scientists from the University of California, Santa Barbara, and Harvard University, demonstrated a technical breakthrough in the oral delivery of insulin, a hormone produced in the pancreas that allows the body to absorb and store sugar from the blood. This discovery is the first step in a longer process to package insulin in a pill that could take many years.

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  • Here’s the 411. Maybe not as much info but it’s free. And not so very earth-shaking, turns out.

    LONDON, May 29 (Reuters) – An experimental diabetes pill from Novo Nordisk proved better at lowering blood sugar levels than Eli Lilly and Boehringer Ingelheim’s established Jardiance in a clinical study, the Danish drugmaker said on Tuesday.

    The success of oral semaglutide in the Phase III trial is a boost for a medicine seen as important for ensuring the group’s long-term growth in a highly competitive diabetes market.

    The once-daily pill, which Novo hopes to launch in 2020, belongs to a blockbuster class of treatments known as GLP-1s that stimulate insulin production. So far, all have been injections and a pill would offer a step-change in convenience.

  • I see I am not alone in commenting adversely on the unconscionable and indefensible practice of the Globe in using my paid subscription to troll for a commercial business seeking a paid subscription by publishing as “news” in the business section a teaser come-on for an undoubtedly newsworthy story.

  • I think this is a scam. As a subscriber, I should be able to read any article in the Globe. But I signed up for the STAT list anyway, followed the link to the web site, and the article was nowhere to be found. Then I noticed a Login button, so I clicked it and it wants a password – even though the signup did not have me set a password. So I clicked “Forgot my password”, which promised a password would be emailed to me. Guess what? No email. Bet I’ll be receiving a whole lot of medical advertising now.

  • This is the one article of any actual relevance to me, and when I attempted to open and fully read it, I was blocked by an extremely irritating popup ad that told me I had to subscribe to STAT in order to be able to read it. What the hell is this about?! I have every right as a Globe subscriber to full, unobstructed access. Get this resolved.

  • Double charging?
    I am a globe subscriber and when I went to read two articles in the online business section today (two of the three highlighted articles) it seems I was required to subscribe to stat to read them. Are you now charging twice to read globe articles? Either include such articles for free or don’t highlight them in your online edition.
    Charging twice is wrong.

  • I was diagnosed with type 2 Diabetes and put on Metformin on June 26th, 2017. I started the some diet and followed it 100% for a few weeks and could not get my blood sugar to go below 140. Finally i began to panic and called my doctor, he told me to get used to it. He said I would be on metformin my whole life and eventually insulin. At that point i knew something wasn’t right and began to do a lot of research. Then I found Lisa’s diabetes story (google ” How I freed myself from diabetes ” ) I read that article from end to end because everything the writer was saying made absolute sense. I started the diet that day and the next week my blood sugar was down to 100 and now i have a fasting blood sugar between Mid 70’s and the 80’s. My doctor took me off the metformin after just three week of being on this lifestyle change. I have lost over 16 pounds and 3+ inches around my waist in a month. The truth is we can get off the drugs and help myself by trying natural methods

  • Lots of physicians and patients have had remarkable success on reversing or halting the progress of diabetes by abstaining from dairy products in particular and animal protein in general. This outcome is predicted by lab and epidemiology as well. I refer you to the work of T. Collin Campbell, PhD.

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