n the good old days — way back in early 2012 — people who contracted gonorrhea were given a single pill to cure the infection. A newly published paper shows that a time is fast approaching when a far more onerous course of medical care may be required to get rid of a bacterium that seems hell-bent on becoming untreatable.

Neisseria gonorrhoeae, the bug that causes gonorrhea, has relentlessly vanquished every antibiotic medical practice has used against it. The current recommended cure — an injection of a drug called ceftriaxone, given in combination with a second antibiotic, azithromycin — is the last good option to treat this infection, and there are already signs that its days may be numbered.

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