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Inside Berkshire Hathaway, some investors think legendary CEO Warren Buffett may be laying the groundwork for a blockbuster business opportunity, spawned from the health care venture he recently formed with the leaders of Amazon and JPMorgan Chase.

While most of the national discussion about the high-profile venture has focused on its potential to reshape the U.S. health care system, interviews with two long-time Berkshire shareholders show that within Buffett World, it’s also seen as a chance to develop profit-making lines of business and new investment ideas.

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The startup itself, led by Dr. Atul Gawande, isn’t intended to make a profit; the CEOs have said it will focus on improving care and lowering costs for their 1.2 million employees. But it will give one of America’s most storied investors an up-close view of a $3.3 trillion sector that Berkshire has scarcely touched, the investors say. After a long career of picking winners in a wide array of other industries, health care could be Buffett’s final act.

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