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AMSTERDAM — A gift of traditional Dutch wooden shoes kicked off the European Union Medicines Agency’s formal move from London to Amsterdam on Wednesday, a concrete consequence of Britain’s looming departure from the bloc.

The process of uprooting hundreds of workers and transferring their lives across the North Sea appears, so far at least, to be going more smoothly than the Brexit divorce between Britain and the EU itself, although the medicines agency still expects to lose about a quarter of its 900 employees.

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