Commonly prescribed oral medications in the U.S. are mostly made up of ingredients that have little to do with the condition being treated, a new study finds. These “inactive” substances, like lactose or gluten, can also be the source of allergies and intolerances.

Dr. Giovanni Traverso, one of the study’s authors, began his research several years ago after hearing about a patient with celiac disease who was prescribed medicine for a different condition. But it turned out that the patient received a formulation of the drug that contained wheat starch as an inactive ingredient, which could lead to an adverse reaction.

Unlock this article by subscribing to STAT Plus and enjoy your first 30 days free!


What is it?

STAT Plus is a premium subscription that delivers daily market-moving biopharma coverage and in-depth science reporting from a team with decades of industry experience.

What's included?

  • Authoritative biopharma coverage and analysis, interviews with industry pioneers, policy analysis, and first looks at cutting edge laboratories and early stage research
  • Subscriber-only networking events and panel discussions across the country
  • Monthly subscriber-only live chats with our reporters and experts in the field
  • Discounted tickets to industry events and early-bird access to industry reports

Leave a Comment

Please enter your name.
Please enter a comment.

  • The ‘other ingredients’ in a tablet or capsule are more properly called ‘excipients’ and they have been a focus point over the last 15 years. Proper quality and control have been an emerging issue. especially as supply chains moved OUS. They are also the reason there is still a role for the compounding industry. It’s a new story to those new to the industry.

Sign up for our Daily Recap newsletter

A roundup of STAT’s top stories of the day in science and medicine

Privacy Policy