Skip to Main Content

Sage Therapeutics is advancing its experimental pill SAGE-217 into a pivotal clinical trial for people with treatment-resistant depression, the company said Wednesday.

Treatment-resistant depression will be the third proposed indication for SAGE-217, a once-daily oral medicine that has already established efficacy in postpartum depression and is being investigated in an ongoing Phase 3 study of major depressive disorder. The Cambridge, Mass.-based company intends to start a Phase 3 study in treatment-resistant depression before the end of the year, said CEO Jeff Jonas said in an interview.

Unlock this article by subscribing to STAT+ and enjoy your first 30 days free!

GET STARTED