Cancer, with all its wiles, has figured out how to withstand science’s best efforts by tapping a secret genetic arsenal. One company aims to kill drug-resistant tumors by cutting off their resupply.

Scores of treatments work by targeting cancer-causing genes like EGFR and HER2. But the trickiest tumors have devised a way to replace the malignant genes by reaching into tiny circles of DNA floating inside cancer cells, allowing tumors to grow despite a pharmaceutical assault. At Boundless Bio, which just raised $46 million in venture funding, the idea is to knock out the backup DNA before cancer can reload.

Unlock this article by subscribing to STAT Plus and enjoy your first 30 days free!

GET STARTED

What is it?

STAT Plus is STAT's premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis. Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond.

What's included?

  • Daily reporting and analysis
  • The most comprehensive industry coverage from a powerhouse team of reporters
  • Subscriber-only newsletters
  • Daily newsletters to brief you on the most important industry news of the day
  • Online intelligence briefings
  • Frequent opportunities to engage with veteran beat reporters and industry experts
  • Exclusive industry events
  • Premium access to subscriber-only networking events around the country
  • The best reporters in the industry
  • The most trusted and well-connected newsroom in the health care industry
  • And much more
  • Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr.

Leave a Comment

Please enter your name.
Please enter a comment.

A roundup of STAT’s top stories of the day in science and medicine

Privacy Policy