Who puts horns on unicorns? How do graying drug companies find green ideas? And what would mice tweet?

We discuss all that and more on the latest episode of “The Readout LOUD,” STAT’s biotech podcast. First, we talk about Ginkgo Bioworks, its multibillion-dollar valuation, and how the age of unicorns is reshaping biotech. Then, Amgen (AMGN) top scientist David Reese stops in to talk about how the storied company is working to ferret out new science to replace its older drugs. Later, James Heathers, the scientist behind @JustSaysInMice, comes by to explain the inspiration behind his mini-viral Twitter account and how it has (arguably) changed scientific discourse online. Finally, we embark upon a lightning round, touching the latest Democratic drug pricing plan, the fortunes of Purdue Pharma, and Martin Shkreli’s business acumen.

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