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Which drug defined the decade? Who’s the worst CEO in biopharma? And how does gene therapy actually work?

We discuss all that and more on the latest episode of “The Readout LOUD,” STAT’s biotech podcast. First, STAT’s Matthew Herper joins us to discuss the most important drugs of the past decade, including treatments for hepatitis C, cystic fibrosis, and cancer. Then, we delve into the holiday tradition that is voting on the best and worst CEOs in biotech. Later, science journalist Karen Weintraub dials in to explain the crucial but little-discussed technology that makes gene therapy work. Finally, the podcast gets self-indulgent as we bid farewell to senior producer Matthew Orr by subjecting him to a lightning round.

For more on what we cover, here are the nominees for best biopharma CEO; here are the ones for worst; and here’s the report on viral vectors.


This podcast is taking the next two weeks off for the holidays, but we’ll be back Thursday, Jan. 9, so be sure to sign up on Apple Podcasts, Stitcher, Google Play, or wherever you get your podcasts.

And if you have any feedback for us — topics to cover, guests to invite, vocal tics to cease — you can email [email protected].


Interested in sponsoring a future episode of “The Readout LOUD”? Email us at [email protected].