In April, AstraZeneca halted a clinical trial of its genetically targeted lung cancer drug Tagrisso based on what it called an “overwhelming benefit” observed in patients with early-stage disease. On Thursday, details from the study were revealed for the first time. AstraZeneca wasn’t exaggerating.
After two years of follow-up, 90% of the lung cancer patients given Tagrisso following surgery were alive without a recurrence of their tumors, doubling the benefit seen with patients offered a placebo. Overall, Tagrisso reduced the risk of lung cancer relapse by 83% compared to placebo — the strongest result ever reported for a clinical trial of this type.