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Freenome, a high-profile startup that aims to develop a blood test to detect colon cancer, has quietly replaced its co-founder and chief executive, Gabriel Otte.

The company’s chief business officer, Mike Nolan, a long-time veteran of the genomics and diagnostic industries, is Freenome’s new CEO. He was identified as such in a Freenome press release on Friday about new data on its experimental test; he is also listed as CEO on Freenome’s website and on his own LinkedIn profile.

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