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What does “one-and-done” treatment actually mean? Do we really need a permanent FDA commissioner? And what’s Scott Gottlieb’s grilling technique?

We cover all that and more this week on “The Readout LOUD,” STAT’s biotech podcast. First, STAT’s Andrew Joseph joins us to talk about the two-year anniversary of the approval of gene therapy Zolgensma and the effect it has had on families dealing with the rare disease spinal muscular atrophy. Then, former FDA Commissioner Scott Gottlieb calls in with tips on Memorial Day grilling, notes on a recent Twitter spat, and thoughts on the origins of SARS-CoV-2.

For more on what we cover, here’s the Zolgensma story; here’s more on how to stay safe at the grill this weekend; here’s where you can subscribe to the First Opinion Podcast; and here’s our complete coverage of the Covid-19 pandemic.

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And if you have any feedback for us — topics to cover, guests to invite, vocal tics to cease — you can email [email protected].

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