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WASHINGTON — Three moderate House Democrats are making good on their threat to oppose Speaker Nancy Pelosi’s aggressive Medicare drug price negotiation, leaving its fate uncertain.

Reps. Scott Peters (Calif.), Kurt Schrader (Ore.) and Kathleen Rice (N.Y.) have publicly stated their intentions to vote down Pelosi’s drug pricing plan as part of the House Energy & Commerce Committee’s markup on a sprawling safety-net package Democrats are advancing this week.

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