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John Maraganore’s decision to step down as Alnylam Pharmaceuticals’ CEO after almost 20 years came as a shock to people outside of the company — enough to send the company’s stock tumbling by more than 16% that day.

But it was a shock, too, to people within Alnylam, Maraganore recalled at the 2021 STAT Summit in Boston on Tuesday. Including, even, his successor as CEO, Yvonne Greenstreet.

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