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Gilead Sciences said Thursday that it has exercised an option to license four cancer drugs from Arcus Biosciences, including an immunotherapy that works against a closely followed anti-cancer target called TIGIT.

In exchange for licensing rights to the four cancer drugs, Gilead is paying Arcus $725 million. The two companies will co-develop the drugs, share costs, and if approved, split profits in the U.S., the companies said.

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For Gilead, the Arcus deal represents another potentially lucrative but risky effort to grow its cancer business, which has struggled to gain traction apart from its bespoke CAR-T therapies.

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