Skip to Main Content
Contribute Try STAT+ Today

ATLANTA — When key mutations strike bone marrow stem cells, known as hematopoietic stem cells, your risk for a litany of diseases go up. “Heart attacks, strokes, more recently COPD, osteoporosis,” Siddhartha Jaiswal, a pathology researcher at Stanford University, rattled off. “And you’re at higher risk of blood cancers in the future. They’re the first hit on the path to cancer.”

These mutations are almost universally bad, Jaiswal said in an interview with STAT. But in a new study, Jaiswal found that these same genetic changes might actually protect against Alzheimer’s disease, startling researchers who reviewed the work and raising questions as to how such pathological mutations could prevent the devastating neurodegenerative disorder. His team presented the new data at the American Society of Hematology annual conference in Atlanta on Sunday.

Unlock this article by subscribing to STAT+ and enjoy your first 30 days free!

GET STARTED

What is it?

STAT+ is STAT's premium subscription service for in-depth biotech, pharma, policy, and life science coverage and analysis. Our award-winning team covers news on Wall Street, policy developments in Washington, early science breakthroughs and clinical trial results, and health care disruption in Silicon Valley and beyond.

What's included?

  • Daily reporting and analysis
  • The most comprehensive industry coverage from a powerhouse team of reporters
  • Subscriber-only newsletters
  • Daily newsletters to brief you on the most important industry news of the day
  • STAT+ Conversations
  • Weekly opportunities to engage with our reporters and leading industry experts in live video conversations
  • Exclusive industry events
  • Premium access to subscriber-only networking events around the country
  • The best reporters in the industry
  • The most trusted and well-connected newsroom in the health care industry
  • And much more
  • Exclusive interviews with industry leaders, profiles, and premium tools, like our CRISPR Trackr.

Create a display name to comment

This name will appear with your comment