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The CAR-T cancer therapy called Carvykti, made by Johnson & Johnson and Legend Biotech, reduced the risk of relapse by 74% compared to standard treatment in patients with multiple myeloma, according to results from a Phase 3 study that leaked online Tuesday night.

The magnitude of the patient benefit reported from the study called CARTITUDE-4 is much better than expected, and if cleared by regulators, will likely persuade doctors to use the personalized cell therapy earlier in the course of treatment of multiple myeloma.


Another CAR-T therapy for multiple myeloma, called Abecma, reduced the risk of relapse by 51% compared to standard treatment in a similar Phase 3 study published last February. Abecma is made by Bristol Myers Squibb and 2Seventy Bio.

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