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The Food and Drug Administration approves dozens of cancer drugs every year, but the vast majority of them offer gradual improvements. A treatment might shrink tumors in a third of patients, or extend survival by a couple months, and a company can still haul in billions.

The results were much more revolutionary when, at six years old, Emily Whitehead became the first child to receive CAR-T cell therapy, in which researchers arm a patient’s own immune cells against their cancer. Whitehead’s therapy almost killed her, but it successfully killed her cancer, paving the way for the approach to become widely available.

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In the decade since, Whitehead’s healthy, ordinary childhood — captured annually in a photo her family releases of Whitehead holding a chalkboard marking eight, nine, 10 years cancer-free — has been a public reminder of what cutting-edge treatments can, sometimes, achieve.

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