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A monkey sits in a cage as two laboratory employees walk by – first opinion coverage from STAT

In its first tough test, CRISPR epigenome editing cuts cholesterol levels in monkeys

May 19, 2023... The Tune Therapeutics results are the first published data showing successful CRISPR epigenome editing in non-human primates.

Drawing of a Scarabaeidae Costelyra zealandica - New Zealand grass grub beetle - Science and chronic disease coverage from STAT

New research may give geneticists a long-sought tool: a targeted protein delivery device

March 29, 2023... New research from a CRISPR pioneer offers a potential solution to delivery challenges that have long stunted genetic medicine.

The manager of BioArt Fertility Clinics lab (L) prepares thawed blastocysts (R) during an in-vitro fertilisation process in Johannesburg, on February 22, 2022.

Mice with two fathers and base-edited baby monkeys highlight potential — and limitations — of hereditable gene editing

March 9, 2023... New research on mice points to the eventual possibility of male-male couples having children who are genetically related to both of them.

New weight loss drugs are changing the narrative on obesity, with a push from pharma

March 5, 2023... A new generation of obesity drugs is transforming patients’ lives, dividing medical experts, and spurring the biggest business battle in years. And pharma is steering the discussion.

This picture taken on November 27, 2018 shows biologist and summit chair David Baltimore (centre R) of the California Institute of Technology speaking at a press conference during the Second International Summit on Human Genome Editing in Hong Kong.

Ahead of genome summit in London, questions linger about CRISPR baby scandal

March 3, 2023... The organizers of the genome summit are still grappling with the fallout of the 2018 CRISPR baby scandal and the ethical debate it ignited.

CRISPR patent fight redux? A new battle is brewing among biotechs over next-gen gene-editing tools

March 1, 2023... The next CRISPR gene-editing patent war might look quite different; it's shaping up to be a free-for-all among a multitude of companies and labs.

How medicine’s revolutionary advances are changing the way we live

Jan. 17, 2023... How precise can gene editing be? Will researchers succeed in extending the “healthspan” of people’s lives? Can telehealth provide responsible mental health care? Do firewalkers hold the key to easing pain? Some of the world’s top biotech researchers, public health experts, and industry executives took on these questions and more at our 2022 STAT Summit,…

David Liu and Jonathan Wosen on the STAT Summit stage.

Perfection is too high a bar for CRISPR treatments, says STAT Biomedical Innovation Award winner David Liu

Nov. 15, 2022... Broad Institute biochemist David Liu was named the recipient of STAT’s 2022 Biomedical Innovation Award at the #STATSummit for expanding the CRISPR gene-editing toolkit.

A person walking up the stair to a brain maze of which a light bulb extends out

Brain implants that translate paralyzed patients’ thoughts into speech creep closer to reality

Nov. 8, 2022... In a new study, a brain implant was able to decode more than 1,100 words from the electrical activity inside a paralyzed patient's brain as he silently tried saying the letters.

After early wins, CRISPR gene editing is about to get a lot harder

Sept. 21, 2022... So far CRISPR has focused on tissues — liver and blood cells — easy for bioengineers to reach. Researchers will have to figure out ways to reach complex areas like muscle safely and efficiently.

Pharmalot Coming/Going STILL

Up and down the ladder: The latest comings and goings

July 22, 2022... From new hires to departures, promotions, and transfers, here are the latest comings and goings in the pharmaceutical industry.

Verve Therapeutics begins human tests of first ‘base editor,’ aiming at heart disease

July 12, 2022... The first patient ever has been dosed with a kind of gene-editing treatment known as a base editor, a newer way of utilizing CRISPR for gene editing.

STAT announces fourth annual 2022 STAT Summit

July 5, 2022... 2022 STAT Summit to feature Pfizer Chairman & CEO, Albert Bourla, Merck Executive Chairman, Ken Frazier, and Eli Lilly Chair & CEO, Dave Ricks BOSTON, MA – Today, STAT, the nation’s must-read health, science, and medicine publication, is proud to announce the 2022 STAT Summit. The two-day, in-person event will take place on November 15-16,…

2022 STAT Summit

June 22, 2022... Nov 15 & 16Boston#STATSummit Get ticketsView Speakers The 2022 STAT Summit is now complete Thank you to the speakers and to all who tuned into our annual flagship Summit event. Be sure to catch up with coverage from the event, and learn more about all of our upcoming Summits. About From trials to triumph: healing…

red brain illo

Four neuroscientists win Kavli Prize for discovering genes behind serious brain disorders

June 1, 2022... Four neuroscientists who discovered the genes involved in a host of serious brain disorders won this year’s $1 million @KavliPrize in neuroscience.

Pharmalot Coming/Going STILL

Up and down the ladder: The latest comings and goings

May 13, 2022... From new hires to departures, promotions, and transfers, here are the latest comings and goings in the pharmaceutical industry.

Hires -- up and down the ladder

Up and down the ladder: The latest comings and goings

March 4, 2022... From new hires to departures, promotions and transfers, here are the latest comings and goings in the pharmaceutical industry.

David Liu

Feb. 16, 2022... In July 2021 Liu raised $315 million to launch Prime Medicine, which aims to use prime editing, a DNA-rewriting method developed in his Broad Institute lab, to treat rare genetic diseases. It’s the sixth startup co-founded by Liu, who has invented multiple tools for precision genetic medicine. Another, Beam Therapeutics, advanced several research programs last…

Pharmalot Coming/Going STILL

Up and down the ladder: the latest comings and goings

Jan. 28, 2022... Here's your rundown of the latest hires, departures, and promotions the pharmaceutical industry.

Pharmalittle: Pfizer makes a major push into mRNA technology; Medicare decision on Alzheimer’s drug may hurt state budgets

Jan. 10, 2022... A preliminary decision on Medicare coverage for the Biogen Alzheimer's drug is due this week, and it has major implications for state Medicaid programs.

Pfizer

Pfizer to pay Beam $300 million in gene-editing deal, amping up its mRNA ambitions

Jan. 10, 2022... A new Pfizer deal with Beam Therapeutics is a loud announcement of the company's interest in base editing for mRNA drug and vaccine development.

Pharmalot Coming/Going STILL

Up and down the ladder: The latest comings and goings

Jan. 7, 2022... From new hires to departures, promotions, and transfers, here are the latest comings and goings in the pharmaceutical industry.

3 to Watch CRISPR

3 CRISPR editing innovations to watch in 2022

Jan. 5, 2022... Here are three emerging CRISPR frontiers that we think it’s worth keeping an eye on in 2022 and beyond.

How Brigham Health helped create a Chinese hospital for elites — and almost nobody came

Dec. 26, 2021... In a deal worth millions with Chinese developer Evergrande, a Harvard teaching hospital risked its reputation on what would become a near-empty shell.

A Eye

Medicine’s first autonomous AI could prevent blindness due to diabetes — if it can reach those most in need

Dec. 16, 2021... “How do we use these new innovative technologies to really mitigate disparities in diabetes outcomes?” asked Risa Wolf, a pediatric endocrinologist at Johns Hopkins Hospital.

Group of scientists management

New CRISPR tools could fix diseases caused by large DNA rearrangements, scientists report

Oct. 14, 2021... The success in mice bolsters hopes that newer generations of genome editors will be able to correct extensive and complicated glitches currently out of reach.

Nobel Medicine

Two scientists win Nobel Prize in medicine for how we sense temperature and touch

Oct. 4, 2021... Two California-based scientists have won the 2021 Nobel Prize in medicine or physiology on Monday for their discoveries of receptors for heat, cold, and touch.

bust of Alfred Nobel

On a day to celebrate the Nobel in medicine, a stain still mars the institute that awards it

Oct. 4, 2021... Medical research — and its oversight — is built on a foundation of trust. Blaming whistleblowers for complicity in the abuses they have reported will have a chilling effect on witnesses coming forward.

Pharmalot Coming/Going STILL

Up and down the ladder: The latest comings and goings

Sept. 24, 2021... From new hires to departures, promotions and transfers, here are the latest comings and goings in the pharmaceutical industry.