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Good morning, everyone, and how are you today? The sun is struggling to peek through the dense clouds covering the Pharmalot campus, where one of the short people and the official mascots are sleeping in. We, however, are pursuing our usual routine of foraging for interesting items. Toward that end, we have collected a few for you. So grab a cup of stimulation as you digest. Meanwhile, hope you have a smashing day and do stay in touch …

Sanofi is ready to raise its $9.3 billion offer to buy Medivation and its Xtandi prostate cancer drug and threatened to launch a hostile bid. “If you are not prepared to engage with us, we have no choice but to go directly to your shareholders,” Sanofi chief executive Olivier Brandicourt wrote to Medivation. “… If the Medivation board continues to refuse to engage with us, then we intend to commence a process to remove and replace members of the board.”


A US Food and Drug Administration advisory panel endorsed mandatory training for doctors who prescribe opioid painkillers, according to the Wall Street Journal. “We need to teach people to use these drugs sparingly,” said Jeanmarie Perrone, a professor of emergency medicine and toxicologist at the University of Pennsylvania, who was one of the panel members. Some physicians have complained FDA education requirements are insufficient.

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