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Good morning, everyone, and how are you today? We are just fine, thank you, now that spring has sprung, although the mounds of snow are quickly transforming the Pharmalot campus into a sloshy mud field. But we will deal with that another time. Right now, it is time to heat up the coffee kettle and get cracking. On that note, here are some tidbits to get your own day underway. Hope you are successful and, as always, please do keep in touch …

Overdoses fell after the Food and Drug Administration implemented a class-wide risk mitigation strategy known as REMS for extended release and long-acting opioid painkillers, but deaths did not, MedPage Today writes, citing a new analysis. As a result, the researchers were not able to determine a cause-and-effect pattern. REMS was approved in 2012 in hopes of reducing serious adverse outcomes from inappropriate prescribing, misuse, and abuse of opioids.

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