s many as 4,100 children were born with major birth defects due to a Sanofi epilepsy drug that was taken by women who were being treated for epilepsy or bipolar disorder, according to a report by the ANSM, the French National Agency for Medicines and Health Products Safety.

Between 1967 and 2016, anywhere from 2,150 to 4,100 children were born with at least one major congenital disorder after being exposed to valproate, which is known as Depakote for treating bipolar disorder and Depakine for treating epilepsy. During that time, between 64,100 and 100,000 pregnancies in France were exposed to the medicine.

Unlock this article by subscribing to STAT Plus today. Try it FREE for 30 days and cancel anytime!


What is it?

STAT Plus is a premium subscription that delivers daily market-moving biopharma coverage and in-depth science reporting from a team with decades of industry experience.

What's included?

  • Authoritative biopharma coverage and analysis, interviews with industry pioneers, policy analysis, and first looks at cutting edge laboratories and early stage research
  • Subscriber-only networking events and panel discussions across the country
  • Monthly subscriber-only live chats with our reporters and experts in the field
  • Discounted tickets to industry events and early-bird access to industry reports

Leave a Comment

Please enter your name.
Please enter a comment.

    • Actually the drug was discovered by French scientists and is marketed in US by Abbott and by Sanofi ex US. You can tell which version is which by the spelling. It is spelled Depakene in the US, and as Depakine ex US.

Sign up for our Morning Rounds newsletter

Your daily dose of what’s new in health and medicine.

Privacy Policy