A

s many as 4,100 children were born with major birth defects due to a Sanofi epilepsy drug that was taken by women who were being treated for epilepsy or bipolar disorder, according to a report by the ANSM, the French National Agency for Medicines and Health Products Safety.

Between 1967 and 2016, anywhere from 2,150 to 4,100 children were born with at least one major congenital disorder after being exposed to valproate, which is known as Depakote for treating bipolar disorder and Depakine for treating epilepsy. During that time, between 64,100 and 100,000 pregnancies in France were exposed to the medicine.

This is a STAT Plus article and you can unlock it by subscribing to STAT Plus today. It's easy! Your first 30 days are free and if you don't enjoy your subscription you can cancel any time.
Already a subscriber? Log in here.

Leave a Comment

Please enter your name.
Please enter a comment.

    • Actually the drug was discovered by French scientists and is marketed in US by Abbott and by Sanofi ex US. You can tell which version is which by the spelling. It is spelled Depakene in the US, and as Depakine ex US.

Sign up for our Biotech newsletter — The Readout

Your daily guide to what’s new in biotech.