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Ongoing controversy over drug prices and a rising number of patent expirations on some big-selling medicines has prompted a downward revision in global sales over the next five years, according to EvaluatePharma, a market research firm.

Last year, the firm forecast global drug sales to hit $1.12 trillion by 2022, but the pharmaceutical landscape is shifting sufficiently to now expect worldwide sales to reach $1.06 trillion. Even so, that represents a healthy 6.5 percent compounded annual growth over the upcoming five-year period.

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