Pfizer plans to close its neuroscience discovery and early development programs, the latest large drug maker to turn its corporate back on developing drugs for central nervous system disorders. As a result, about 300 jobs are being eliminated from three different Pfizer locations — Cambridge and Andover, Mass., and Groton, Conn.

The programs were primarily focused on Alzheimer’s and Parkinson’s disease, according to a Pfizer spokesman. As of Oct. 31, a Pfizer web page that is no longer visible listed nine neuroscience projects under way — six that were in Phase 1, two more in Phase 2, and another in Phase 3.

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