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Two former Insys Therapeutics sales employees have agreed to cooperate with a federal government probe that prosecutors have described as a “nationwide conspiracy” to profit from illegally distributing an opioid medication.

Jonathan Roper, a former district sales manager, and Fernando Serrano, a former sales representative, also pleaded guilty to paying kickbacks to doctors in order to boost prescriptions for the Subsys painkiller, which contains fentanyl, a powerful and addictive opioid, prosecutors said Friday. In addition, the feds disclosed indictments of five New York doctors for taking kickbacks.

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