Hello, everyone, and welcome to the middle of the week. You made it this far, so why not continue, yes? Perhaps a cup or two of stimulation is in order. We are blending butter pecan and pumpkin spice today, since we enjoy early-stage scientific experiments. Feel free to indulge your own caffeine fantasies as you attack the laundry list of meetings and deadlines that await. Meanwhile, we have once again assembled a list of tidbits for you to peruse and help you on your way. Hope you have a smashing day and, as always, do drop us a line when you hear something interesting.

A former Takeda Pharmaceuticals (TKPYY) chairman is voicing opposition to the proposed $62 billion acquisition of Shire (SHPG), breaking a long silence, The Nikkei Asian Review reports. Mergers and acquisitions are necessary in the pharmaceutical industry, “but the Shire deal’s risk is high,” says Kunio Takeda. His comments come ahead of a Dec. 5 shareholder meeting to approve the deal. Takeda, 78, held leadership positions with the company such as president and chairman from 1993 to 2009, overseeing a period of fast growth.

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