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Good morning, everyone, and how are you today? Some puffy clouds are hovering over the Pharmalot campus, but our spirits remain sunny. After all, as the Morning Mayor used to say, “Every brand new day should be unwrapped like a precious gift.” So while you tug on the ribbon, we will concoct another cup of needed stimulation. A change of pace is in order and so our choice this morning is hot buttered rum. Feel free to join us. Meanwhile, we have gathered a few tidbits to help you along. Hope all goes well today and please do stay in touch …

Vertex Pharmaceuticals (VRTX) says Ian Smith, who was executive vice president, chief operating officer, and interim chief financial officer, was terminated due to “personal behavior” that violated its “code of conduct and values,” but that this was “unrelated to our financial and business performance.” Paul Silva, senior vice president and corporate controller, was appointed interim chief financial officer. The move followed an investigation by the Wilmer Cutler Pickering Hale & Dorr law firm, The Boston Globe adds. Smith joined Vertex in 2001 from Ernst & Young.

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