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As a landmark trial over the opioid crisis grows closer, Endo International (ENDP) agreed to a $10 million settlement with two Ohio counties that claimed the drug maker contributed to the problem by inappropriately marketing its addictive painkillers.

The trial, which is scheduled to begin in Oct. 21, will be the first to test arguments made by numerous cities, counties, Native American tribes, and still others that several drug makers and distributors fomented the crisis. Some 2,000 lawsuits have been combined in a massive litigation in a federal court in Cleveland, where a judge has been urging a settlement.

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