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Good morning, everyone, and how are you today? We are doing just fine, thank you, despite a drop of snow that has descended on the frosty Pharmalot campus. No matter. We have managed to dispense with the white stuff, fire up the coffee kettle, and even assemble the below list of items of interest. This is why a few cups of stimulation are in order. Our choice today is hot-buttered rum, for those who track this sort of thing or wish to experiment. In any event, have a lovely day, stay warm and, as always, do keep in touch.

In the early days of OxyContin, Dr. Richard Sackler, a member of the Sackler family who founded and controls Purdue Pharma, learned about concerns the potent opioid could lead to abuse in chronic pain patients, and he then proposed executives aggressively push back, according to newly unsealed documents obtained by STAT. In emails, he said executives should consider giving a “convincing presentation” that controlled-release products like OxyContin are “less prone to addiction potential, abuse or diversion” than other opioid pain pills.

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