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Good morning, everyone, and welcome to another working week. We hope the weekend respite was somehow relaxing and refreshing, given the dizzying developments outside your window. Now, of course, the relentless routine of Zoom meetings, Skype calls, and deadlines has returned, so time to get cracking. We are firing up the coffee kettle to brew another cup of stimulation — cinnamon mocha is our choice today — and, as always, we invite you to join us. Meanwhile, here is the latest menu of tidbits to help you get going. We hope today is productive, and meanwhile, stay safe — wear a mask. …

Pfizer (PFE) and its partner BioNTech (BNTX) reported that their Covid-19 vaccine was strongly effective, exceeding expectations with results that are likely to be met with cautious excitement — and relief — in the face of the global pandemic, STAT tells us. The vaccine is the first to be tested in the U.S. to generate late-stage data. The companies said an early analysis of results showed individuals who received two injections three weeks apart experienced more than 90% fewer cases of symptomatic Covid-19 than those who received a placebo.


President-elect Joe Biden’s health-care advisers have held talks with pharmaceutical-industry executives in which they discussed Operation Warp Speed, according to Bloomberg News. Biden advisers met with companies that have Covid-19 vaccines or therapies in late-stage clinical trials in September and October, and the purpose was to gather information about the development, manufacturing, and distribution of shots to ward off the novel coronavirus and therapies to treat the sick.

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