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And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is decidedly modest. We hope to catch up on our reading, sprint with the official mascot, and otherwise hang about. And what about you? Those of you on this side of the pond could start preparing your taxes. You could check to see how long it may be before you can get vaccinated or reach out to someone feeling isolated. Maybe a good nap is in order. Well, whatever you do, have a grand time. But be safe — wear a mask. Enjoy, and see you soon. …

Johnson & Johnson (JNJ) reported its single-dose Covid-19 vaccine reduced rates of moderate and severe disease, but appeared less effective in South Africa, where a new variant has become common, STAT writes. Overall, the vaccine was 66% effective 28 days after vaccination. But efficacy differed depending on geography. The shot was 72% effective among clinical trial volunteers in the U.S, but 66% in Latin America, and just 57% in South Africa. Though below levels seen with the first two authorized vaccines, the rates are above thresholds set by the Food and Drug Administration to be considered useful.

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