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And so, another working week will soon draw to a close. Not a moment too soon, yes? This is, you may recall, our treasured signal to daydream about weekend plans. Our agenda is rather modest. We have bold plans to train the official mascot (taking in the mail would be a good start), catch up on our reading, and stroll about town in hopes of enjoying the great outdoors. And what about you? This is a good time to start your spring cleaning. You could engage in a little online shopping to spur the economy. Or you could make that vaccine appointment. Well, whatever you do, have a grand time. But be safe — wear a mask. Enjoy, and see you soon. …

A rheumatoid arthritis drug from Eli Lilly (LLY) and Incyte (INCY) did not meet the main goal of preventing progression to mechanical ventilation in a late-stage study in hospitalized Covid-19 patients, BioPharmaDive says. Roughly 8% of participants given baricitinib along with standard of care died by day 28 of the trial versus 13.1% on a placebo, a 38% reduction. In a somewhat paradoxical result, however, Lilly said its drug substantially reduced the risk of death by any cause in the trial. Baricitinib was authorized for emergency use in combination with remdesivir for Covid-19 patients needing supplemental oxygen.

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