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After two years of contentious bargaining, a U.S. bankruptcy court judge on Wednesday approved a controversial plan that will dissolve Purdue Pharma, which has been blamed for triggering a widespread opioid crisis, and shield members of the Sackler family who control the company from future lawsuits.

The settlement calls for some Sackler family members to contribute more than $4.3 billion over nearly a decade to compensate people, local governments, and tribal communities that were harmed by the OxyContin painkiller. Another $175 million will be contributed after the Sackler family members relinquish control of several charitable institutions.

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